Glutathione Peroxidase 1 (GPX1) (130-142) Goat Polyclonal Antibody

CAT#: AP22871PU-N

Glutathione Peroxidase 1 (GPX1) (130-142) goat polyclonal antibody, Aff - Purified

Product Images

Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with GPX1 antibody at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

• 

  Human Liver (formalin-fixed, paraffin-embedded) stained with GPX1 antibody at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/32000.
  Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
  Western Blot: 1 - 3 µg/ml.
• Reactivities: Equine, Human, Monkey
• Host: Goat
• Clonality: Polyclonal
• Immunogen: GPX1 antibody was raised against synthetic peptide from an internal region of human GPX1
• Specificity: This antibody reacts to Glutathione Peroxidase (GPX1) at aa 130-142.
• Formulation: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens glutathione peroxidase 1 (GPX1), transcript variant 1
• Database Link:
  Entrez Gene 2876 Human
• Background: GPX1 / Glutathione Peroxidase is a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon.
• Synonyms: GSHPx-1, Cellular glutathione peroxidase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Arachidonic acid metabolism, Glutathione metabolism, Huntington's disease