Ezrin (EZR) (352-363) Goat Polyclonal Antibody

CAT#: AP22873PU-N

Ezrin (EZR) (352-363) goat polyclonal antibody, Aff - Purified

Product Images

Human Colon (formalin-fixed, paraffin-embedded) stained with EZR antibody at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Kidney (formalin-fixed, paraffin-embedded) stained with EZR antibody at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/16000.
  Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
  Western Blot: 1 - 3 µg/ml.
• Reactivities: Human, Monkey
• Host: Goat
• Clonality: Polyclonal
• Immunogen: EZR antibody was raised against synthetic peptide from an internal region of human EZR
• Specificity: This antibody reacts to Ezrin (EZR) at aa 352-363.
• Formulation: Tris buffered saline containing 0.5% BSA and 0.02% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ezrin (EZR), transcript variant 2
• Database Link:
  Entrez Gene 7430 Human
• Background: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene.
• Synonyms: p81, Cytovillin, Villin-2, EZR, VIL2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton