PDK1 Rabbit Polyclonal Antibody

CAT#: AP22886PU-N

PDK1 rabbit polyclonal antibody, Purified

Product Images

Western Blot Analysis of PDK1: Lane 1: MWM Lane 2: HeLa Lane 3: Rat Brain Lane 4: Mouse Brain Lane 5: Vero Lane 6: ESK-4 Lane 7: RK-13 Lane 8: MDCK

• 

  Skeletal muscle. Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/1000.
• Reactivities: Canine, Human, Monkey, Mouse, Porcine, Rabbit, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Fusion protein containing amino acids 269-320 from human m1 AChR.
• Specificity: This antibody reacts to Pyruvate Dehydrogenase Kinase Isoenzyme 1 (PDK1).
• Formulation: PBS containing 0.09% azide and 50% glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens pyruvate dehydrogenase kinase 1 (PDK1), transcript variant 2
• Database Link:
  Entrez Gene 116551 RatEntrez Gene 228026 MouseEntrez Gene 5163 Human
• Background: PDK1 belongs to the PDK/BCKDK protein kinase subfamily. PDK1 contributes to the regulation of glucose metabolism by inhibiting the mitochondrial pyruvate dehyrogenase complex by phosphorylating the E1 alpha subunit.
• Synonyms: Pyruvate dehydrogenase kinase isoform 1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Fc epsilon RI signaling pathway, Neurotrophin signaling pathway, T cell receptor signaling pathway