DAP12 (TYROBP) (Internal) Goat Polyclonal Antibody

CAT#: AP22905PU-N

DAP12 (TYROBP) (Internal) goat polyclonal antibody, Aff - Purified

Product Images

Human Spleen (formalin-fixed, paraffin-embedded) stained with TYROBP antibody followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Uterus (formalin-fixed, paraffin-embedded) stained with TYROBP antibody followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 3 - 6 µg/ml.
• Reactivities: Bat, Canine, Equine, Human, Monkey
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide C-KQRITETESPYQE from an internal region of human TYROBP / DAP12 (NP_003323.1; NP_937758.1)
• Specificity: This antibody reacts to Tyro Protein Tyrosine Kinase Binding Protein (TYROBP) at Internal region.
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens TYRO protein tyrosine kinase binding protein (TYROBP), transcript variant 1
• Database Link:
  Entrez Gene 7305 Human
• Background: DAP12 is a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element.
• Synonyms: KARAP

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity