SPI1 (27-37) Goat Polyclonal Antibody

CAT#: AP22967PU-N

SPI1 (27-37) goat polyclonal antibody, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications IHC
Recommended Dilution Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Reactivities Bovine, Canine, Equine, Human, Porcine, Rabbit
Host Goat
Clonality Polyclonal
Immunogen Synthetic peptide from an internal region of human SPI1 / PU.1 (NP_001074016.1; NP_003111.2)
Specificity This antibody reacts to the internal region of Spi-1 Proto-oncogene (SPI1).
Formulation Tris saline buffer, pH 7.3 containing 0.5% BSA and 0.02% sodium azide
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration 0.5 mg/ml
Purification Immunoaffinity Chromatography
Gene Name Homo sapiens Spi-1 proto-oncogene (SPI1), transcript variant 2
Background Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.
Synonyms Transcription factor PU.1, SPI-1 proto-oncogene, SFPI1
Reference Data
Protein Families Transcription Factors
Protein Pathways Acute myeloid leukemia, Pathways in cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.