DDX58 Goat Polyclonal Antibody

CAT#: AP22979PU-N

DDX58 goat polyclonal antibody, Aff - Purified

Product Images

Spleen, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: DDX58 antibody was raised against synthetic peptide from human DDX58 / RIG-1 / RIG-I
• Specificity: This antibody reacts to RNA Helicase (RIG-I) (DDX58).
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA and 0.02% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens DEXD/H-box helicase 58 (DDX58)
• Database Link:
  Entrez Gene 23586 Human
• Background: EAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.
• Synonyms: RIG-1, RIG-I, DKFZp434J1111, DKFZp686N19181, FLJ13599, DEAD box protein 58

Reference Data

• Protein Pathways: Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway