TNFAIP3 Goat Polyclonal Antibody

CAT#: AP22993PU-N

TNFAIP3 goat polyclonal antibody, Aff - Purified

Product Images

Small intestine, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Human, Monkey, Rabbit
• Host: Goat
• Clonality: Polyclonal
• Immunogen: TNFAIP3 antibody was raised against synthetic peptide from human TNFAIP3 / A20.
• Specificity: This antibody reacts to Tumor Necrosis Factor, Alpha-induced Protein 3 (TNFAIP3).
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA and 0.02% sodium azide
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens TNF alpha induced protein 3 (TNFAIP3), transcript variant 3
• Database Link:
  Entrez Gene 7128 Human
• Background: Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Involved in immune and inflammatory responses signaled by cytokines, such as TNF-alpha and IL-1 beta, or pathogens via Toll-like receptors (TLRs) through terminating NF-kappa-B activity. Essential component of a ubiquitin-editing protein complex, comprising also RNF11, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways.
• Synonyms: OTUD7C, Zinc finger protein A20

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: NOD-like receptor signaling pathway