TRF2 (TERF2) Goat Polyclonal Antibody
Other products for "TERF2"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | Immunohistochemistry on Paraffin Sections: 3.75 µg/ml. |
Reactivities | Bat, Bovine, Canine, Equine, Human, Monkey, Porcine |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Synthetic peptide from human TERF2 / TRF2 |
Specificity | This antibody reacts to Telomeric Repeat Binding Factor 2 (TERF2). |
Formulation | Tris saline buffer, pH 7.3 containing 0.5% BSA and 0.02% sodium azide State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Immunoaffinity Chromatography |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens telomeric repeat binding factor 2 (TERF2) |
Database Link | |
Background | Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. |
Synonyms | TRBF2, TRF2 |
Reference Data | |
Protein Families | Transcription Factors |
Documents
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