HDAC2 (N-term) Rabbit Polyclonal Antibody

CAT#: AP23017PU-N

HDAC2 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Jurkat nuclear extract was resolved by electrophoresis, transferred to nitrocellulose and probed with rabbit anti-HDAC2 antibody. Proteins were visualized using a donkey anti-rabbit secondary conjugated to HRP and a chemiluminescence detection system.

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  IHC Image for Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  IHC Image of Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 20 µg/ml.
  Western Blot.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant mouse HDAC2
• Specificity: This antibody reacts to Histone Deacetylase 2 (HDAC2)
• Formulation: Phosphate-buffered solution, pH 7.2 containing 0.09% sodium azide, 50% glycerol
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store the antibody (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens histone deacetylase 2 (HDAC2), transcript variant 1
• Database Link:
  Entrez Gene 15182 MouseEntrez Gene 3066 Human
• Background: Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
• Synonyms: Histone deacetylase 2, HD2

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transcription Factors
• Protein Pathways: Cell cycle, Chronic myeloid leukemia, Huntington's disease, Notch signaling pathway, Pathways in cancer