SH3BP1 (689-701) Goat Polyclonal Antibody

CAT#: AP23028PU-N

SH3BP1 (689-701) goat polyclonal antibody, Aff - Purified

Product Images

Western Blot Image: Antibody staining (1 ug/ml) of Human Brain lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

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  Immunohistochemistry Image: Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunohistochemistry Image: Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/16000.
  Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot: 1 - 3 µg/ml.
• Reactivities: Human, Monkey
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from C-terminus of human SH3BP1
• Specificity: This antibody detects SH3BP1 (C-term).
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity chromatography
• Gene Name: Homo sapiens SH3 domain binding protein 1 (SH3BP1)
• Database Link:
  Entrez Gene 23616 Human
• Background: Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.
• Synonyms: SH3 domain-binding protein 1, SH3BP-1, 3BP1, 3BP-1