Thrombin Receptor (F2R) (24-37) Goat Polyclonal Antibody

CAT#: AP23067PU-N

Thrombin Receptor (F2R) (24-37) goat polyclonal antibody, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

Product Images

Specifications

Product Data
Applications ELISA, IHC, WB
Recommended Dilution ELISA: 1/3200.
Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
Western Blot: 0.5 - 2 µg/ml.
Reactivities Human
Host Goat
Clonality Polyclonal
Immunogen Synthetic peptide from the Internal region (near N-terminus) of the human protein sequence according to NP_001983.2
Specificity This antibody detects Thrombin receptor / F2R at internal region (near N-terminus).
Formulation Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Immunoaffinity Chromatography
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens coagulation factor II thrombin receptor (F2R), transcript variant 1
Background Thrombin Receptor is a Proteinase-Activated Receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. Thrombin induced RANTES expression through a PAR-1 mediated pathway influences inflammatory cell migration to the synovium in patients with rheumatoid arthritis.
Synonyms Proteinase-activated receptor 1, PAR-1, PAR1, CF2R
Reference Data
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Calcium signaling pathway, Complement and coagulation cascades, Endocytosis, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.