CCR4 (Extracell. Dom.) Goat Polyclonal Antibody

CAT#: AP23074PU-N

CCR4 (Extracell. Dom.) goat polyclonal antibody, Aff - Purified

Product Images

Pancreas, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, FC, IHC, WB
• Recommended Dilution: ELISA: 1/30000.
  Flow Cytometry: 1/12.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500.
• Reactivities: Human, Monkey
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic corresponding to Human CCR4 extracellular domain.
  Epitope: Extracellular Domain.
• Specificity: This antibody detects CD194 / CCR4 (Extracell. Dom).
  Peptide sequence is < 50% identical to other chemokine receptors in this region.
• Formulation: 10 mM KHPO4, 140 mM NaCl
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Stabilizer: 1 mg/ml BSA
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage:

  Store (in aliquots) at -20°C to -80°C.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens C-C motif chemokine receptor 4 (CCR4)
• Database Link:
  Entrez Gene 705457 MonkeyEntrez Gene 1233 Human
• Background: CCR4, a Chemokine Receptor, mediates inflammatory responses and HIV-1 infections. It binds beta-family chemokines (CC motif) such as TARC (thymus and activation-regulated chemokine) and MDC (macrophage-derived chemokine).
• Synonyms: C-C chemokine receptor type 4, C-C CKR-4, CC-CKR-4, CCR-4, CMKBR4, K5-5

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction