SFRP1 (302-314) Goat Polyclonal Antibody

CAT#: AP23107PU-N

SFRP1 (302-314) goat polyclonal antibody, Aff - Purified

Product Images

SFRP1 Antibody staining of Formalin-Fixed, Paraffin-Embedded HUman Kidney at 3.75 ug/ml after heat-induced antigen retrieval.

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  SFRP1 Antibody staining of Formalin-Fixed, Paraffin-Embedded HUman Uterus at 3.75 ug/ml after heat-induced antigen retrieval.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Bovine, Equine, Human, Monkey, Mouse, Rat
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from the C-terminus of Human SFRP1 (NP_003003.3)
• Specificity: This antibody recognizes SFRP1 (C-term).
• Formulation: Tris saline, pH~.3
  State: Aff - Purified
  State: Liquid purfied Ig fraction
  Stabilizer: 0.5% BSA
  Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens secreted frizzled related protein 1 (SFRP1)
• Database Link:
  Entrez Gene 20377 MouseEntrez Gene 84402 RatEntrez Gene 6422 Human
• Background: SARP2 is a frizzled protein that lacks the 7-transmembrane motif used as anchor to the plasma membrane. Expression of SARP2 modifies the intracellular levels of beta-catenin, a molecule involved in the Wnt-frizzled signaling pathway. SARP2-expressing cells are more sensitive to apoptotic stimuli. SARP2 is expressed in several human tissues, with the highest levels in heart.
• Synonyms: SFRP-1, FRP-1, FRP1, FRP, SARP2, SARP-2

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway, Transmembrane
• Protein Pathways: Wnt signaling pathway