SFRP1 (171-183) Goat Polyclonal Antibody

CAT#: AP23110PU-N

SFRP1 (171-183) goat polyclonal antibody, Aff - Purified

Product Images

Uterus, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Bat, Bovine, Canine, Equine, Human, Monkey, Rat
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of human SFRP1 (NP_003003.3)
• Specificity: This antibody detects SFRP1 (Internal).
• Formulation: Tris saline, pH 7.3 containing 0.02% sodium azide as preservative and 0.5% BSA as stabilizer
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens secreted frizzled related protein 1 (SFRP1)
• Database Link:
  Entrez Gene 84402 RatEntrez Gene 6422 Human
• Background: SARP2 is a frizzled protein that lacks the 7-transmembrane motif used as anchor to the plasma membrane. Expression of SARP2 modifies the intracellular levels of beta-catenin, a molecule involved in the Wnt-frizzled signaling pathway. SARP2-expressing cells are more sensitive to apoptotic stimuli. SARP2 is expressed in several human tissues, with the highest levels in heart.
• Synonyms: SFRP-1, FRP-1, FRP1, FRP, SARP2, SARP-2

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway, Transmembrane
• Protein Pathways: Wnt signaling pathway