CYP26A1 (485-496) Goat Polyclonal Antibody

CAT#: AP23113PU-N

CYP26A1 (485-496) goat polyclonal antibody, Aff - Purified

Product Images

Brain, cerebellum, white matter, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

  Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of human CYP26A1 (NP_000774.2; NP_476498.1)
• Specificity: This antibody detects CYP26A1 (Internal).
  It is expected to recognize both reported isoforms (NP_000774.2; NP_476498.1).
• Formulation: Tris saline, pH 7.3 containing 0.02% sodium azide as preservative and 0.5% BSA as stabilizer
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens cytochrome P450 family 26 subfamily A member 1 (CYP26A1), transcript variant 1
• Database Link:
  Entrez Gene 1592 Human
• Background: CYP26 / CYP26A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities.
• Synonyms: Cytochrome P450 26A1, CYP26, Cytochrome P450RAI1

Reference Data

• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Retinol metabolism