Fatty Acid Synthase (FASN) (2118-2129) Goat Polyclonal Antibody

CAT#: AP23118PU-N

Fatty Acid Synthase (FASN) (2118-2129) goat polyclonal antibody, Aff - Purified

Product Images

Brain, cerebellum, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

  Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from internal region of human FASN (NP_004095.4)
• Specificity: This antibody detects Fatty acid synthase (Internal).
• Formulation: Tris saline, pH 7.3 containing 0.02% sodium azide as preservatice and 0.5% BSA as stabilizer
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens fatty acid synthase (FASN)
• Database Link:
  Entrez Gene 2194 Human
• Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
• Synonyms: FASN, FAS

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Fatty acid biosynthesis, Insulin signaling pathway, Metabolic pathways