Two pore calcium channel protein 2 (TPCN2) (735-747) Goat Polyclonal Antibody

CAT#: AP23140PU-N

Two pore calcium channel protein 2 (TPCN2) (735-747) goat polyclonal antibody, Aff - Purified

Product Images

Colon, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Pancreas, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from the C-terminus of human TPCN2 (NP_620714.2)
• Specificity: This antibody detects TPCN2 (C-term).
• Formulation: Tris saline, pH 7.3 containing 0.02% sodium azide as preservative and 0.5% BSA as stabilizer
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens two pore segment channel 2 (TPCN2)
• Database Link:
  Entrez Gene 219931 Human
• Background: TPC2 / TPCN2 is a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.
• Synonyms: Two pore calcium channel protein 2, TPC2

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other