Alkyl DHAP synthase (AGPS) (370-628) Rabbit Polyclonal Antibody

CAT#: AP23156PU-N

Alkyl DHAP synthase (AGPS) (370-628) rabbit polyclonal antibody, Aff - Purified

Product Images

Sample (30 ug of whole cell lysate). A:Raji. 7.5% SDS PAGE. AGPS antibody diluted at 1:1500.

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  Sample (30 ug of whole cell lysate). A: NIH-3T3. 7.5% SDS PAGE. Alkyl-DHAP synthase antibody. AGPS antibody diluted at 1:1000.

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  Human Brain, cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/500 - 1/3000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 370 and 628 of Alkyl-DHAP synthase
• Specificity: This antibody detects AGPS / AAG5 at aa 370-628.
• Formulation: PBS, pH 7, 40% Glycerol, 0.01% Thimerosal
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: 1 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens alkylglycerone phosphate synthase (AGPS)
• Database Link:
  Entrez Gene 84114 RatEntrez Gene 228061 MouseEntrez Gene 8540 Human
• Background: Alkylglycerone phosphate synthase (AGPS) belongs to a group of peroxisomal enzymes that catalyze the first step in ether phospholipid biosynthesis which involves the acylation of dihydroxyacetonephosphate followed by the introduction of the ether linkage by alkyl-DHAP synthase. Human AGPS shares a 92% nucleotide and amino acid sequence similarity with the guinea pig sequences, and the human sequence was identified by virtue of this homology. Both proteins contain identical peroxisomal targeting signal 2 sequences in their N-terminal presequences. Deficiency of AGPS in peroxisomes has been found in patients with the following peroxisomal disorders: Zellweger syndrome, rhizomelic chondrodysplasia punctate and adrenoleukodystrophy.
• Synonyms: Alkyl-DHAP synthase

Reference Data

• Protein Pathways: Ether lipid metabolism, Metabolic pathways