CAD 1625-1900 Rabbit Polyclonal Antibody

CAT#: AP23157PU-N

CAD 1625-1900 rabbit polyclonal antibody, Aff - Purified

Product Images

Sample (30 ug whole cell lysate). A:293T whole cell lysate. 5% SDS PAGE. CAD antibody diluted at 1:1500

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  Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/500 - 1/3000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1625 and 1900 of Human CAD
• Specificity: This antibody detects CAD Protein at aa 1625-1900.
• Formulation: PBS, pH 7, 10% Glycerol, 0.01% Thimerosal
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Purification: Immunoaffinity Chromatography
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: Homo sapiens carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD), transcript variant 1
• Database Link:
  Entrez Gene 24240 RatEntrez Gene 69719 MouseEntrez Gene 790 Human
• Background: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase.
• Synonyms: Dihydroorotase, GATase, ACTase, DHOase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alanine, aspartate and glutamate metabolism, Metabolic pathways, Pyrimidine metabolism