CACNG5 (43-296) Rabbit Polyclonal Antibody

CAT#: AP23174PU-N

CACNG5 (43-296) rabbit polyclonal antibody, Aff - Purified

Product Images

Sample (30 ug whole cell lysate). A:Hep G2. 12% SDS PAGE. CACNG5 antibody diluted at 1:1000

• 

  Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/500 - 1/3000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 43 and 296 of Human CACNG5
• Specificity: This antibody detects CACNG5 at 43-296.
• Formulation: 0.1 M Tris-glycine, pH 7, 10% Glycerol, 0.01% Thimerosal
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: 1 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 5 (CACNG5)
• Database Link:
  Entrez Gene 140723 MouseEntrez Gene 140726 RatEntrez Gene 27091 Human
• Background: Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state.
• Synonyms: MGC126656; MGC126682

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway