EAAT1 (SLC1A3) (C-term) Rabbit Polyclonal Antibody

CAT#: AP23255PU-N

EAAT1 (SLC1A3) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of rat pancreas tissue lysis using GLAST antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: At 0.5-1μg/ml with the appropriate system to detect glast in cells and tissues.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a sequence at the C-terminal of the human Glast
• Specificity: This antibody detects SLC1A3 / EAAT1 at C-term.
• Formulation: 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: 0.2ml of distilled water will yield a concentration of 500μg/ml.
• Purification: Immunogen affinity purified
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens solute carrier family 1 (glial high affinity glutamate transporter), member 3 (SLC1A3), transcript variant GLAST
• Database Link:
  Entrez Gene 20512 MouseEntrez Gene 29483 RatEntrez Gene 6507 Human
• Background: Glast, also known as EAAT1. EAAT1 (SLC1A3) is a member of a family of high-affinity sodium-dependent transporter molecules that regulate neurotransmitter concentrations at the excitatory glutamatergic synapses of the mammalian central nervous system. human GLAST1 gene contains 10 exons spanning at least 85 kb. EAAT1 gene is mapped to chromosome 5p13. GLAST is required for normal signal transmission between photoreceptors and bipolar cells and that both GLAST and GLT-1 play a neuroprotective role during ischemia in the retina. Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures.
• Synonyms: GLAST, GLAST1, GLAST-1

Reference Data

• Protein Families: Transmembrane