EAAT1 (SLC1A3) (C-term) Rabbit Polyclonal Antibody

CAT#: AP23255PU-N

EAAT1 (SLC1A3) (C-term) rabbit polyclonal antibody, Aff - Purified


USD 405.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Applications WB
Recommended Dilution Western blot: At 0.5-1μg/ml with the appropriate system to detect glast in cells and tissues.
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a sequence at the C-terminal of the human Glast
Specificity This antibody detects SLC1A3 / EAAT1 at C-term.
Formulation 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
State: Aff - Purified
State: Lyophilized Ig fraction
Reconstitution Method 0.2ml of distilled water will yield a concentration of 500μg/ml.
Purification Immunogen affinity purified
Storage Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens solute carrier family 1 (glial high affinity glutamate transporter), member 3 (SLC1A3), transcript variant GLAST
Background Glast, also known as EAAT1. EAAT1 (SLC1A3) is a member of a family of high-affinity sodium-dependent transporter molecules that regulate neurotransmitter concentrations at the excitatory glutamatergic synapses of the mammalian central nervous system. human GLAST1 gene contains 10 exons spanning at least 85 kb. EAAT1 gene is mapped to chromosome 5p13. GLAST is required for normal signal transmission between photoreceptors and bipolar cells and that both GLAST and GLT-1 play a neuroprotective role during ischemia in the retina. Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures.
Synonyms GLAST, GLAST1, GLAST-1
Reference Data
Protein Families Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.