Apoptosis inhibitor 5 (API5) (C-term) Rabbit Polyclonal Antibody

CAT#: AP23281PU-N

Apoptosis inhibitor 5 (API5) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of rat cardiac tissue lysis using API5 antibody AP23281PU-N

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  Immunohistochemical analysis of paraffin embedded Human epidermic carinoma sections using API5 antibody AP23281PU-N

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: At 1-2μg/ml with the appropriate system to detect API5 in cells and tissues.
  Immunohistochemistry on paraffin sections: At 0.5-1μg/ml to detect API5 in formalin fixed and paraffin embedded tissues. Boiling the sections is required.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a sequence at the C-terminal of human API5
• Specificity: This antibody detects API5 / MIG8 at C-term.
• Formulation: 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: 0.2ml of distilled water will yield a concentration of 500μg/ml.
• Purification: Affinity-chromatography using epitope-specific immunogen
• Gene Name: Homo sapiens apoptosis inhibitor 5 (API5), transcript variant 2
• Database Link:
  Entrez Gene 11800 MouseEntrez Gene 362170 RatEntrez Gene 8539 Human
• Background: Many growth factors and cytokines act as cellular survival factors by preventing programmed cell death (apoptosis). Apoptosis inhibitor 5 (API5) is an antiapoptotic factor which may have a role in protein assembly. It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription.
• Synonyms: Protein XAGL, FIF, AAC-11

Reference Data

• Protein Families: Druggable Genome