BDNF Rabbit Polyclonal Antibody

CAT#: AP23288PU-N

BDNF rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of brain tissue lysate using BDNF antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1-2μg/ml with the appropriate system to detect BDNF in cells and tissues.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide mapping at the middle region of human BDNF
• Specificity: This antibody detects BDNF (mid region). No cross reactivity with other proteins.
• Formulation: 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: 1.2% sodium acetate or neutral PBS. If 0.5ml of PBS is used, the antibody concentration will be 0.1 mg/ml.
• Purification: Immunogen affinity purified
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 7
• Database Link:
  Entrez Gene 12064 MouseEntrez Gene 24225 RatEntrez Gene 627 Human
• Background: Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT3, and NT4. BDNF is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain.BDNF is expressed within peripheral ganglia and is not restricted to neuronal target fields. BDNF has been purified and shown to reduce the amount of naturally occurring neuronal cell death in portions of the peripheral nervous system.
• Synonyms: Brain-derived neurotrophic factor, Abrineurin

Reference Data

• Protein Families: Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Secreted Protein, Transmembrane
• Protein Pathways: Huntington's disease, MAPK signaling pathway, Neurotrophin signaling pathway