CD71 (TFRC) (C-term) Rabbit Polyclonal Antibody

CAT#: AP23306PU-N

CD71 (TFRC) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of rat spleen sections using CD71 antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1 μg/ml.
  Immunohistochemistry on Paraffin Sections: 1 μg/ml (Antigen Retrieval by heat is required).
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a sequence at the C-terminal of Human CD71
• Specificity: This antibody detects CD71 / TFRC at C-term.
  No cross reactivity with other proteins.
• Formulation: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide
  State: Aff - Purified
  State: Lyophilized purified Ig fraction
• Reconstitution Method: Restore with 0.2 ml of distilled water to a concentration of 0.5 mg/ml.
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody after reconstitution at 2-8°C for one month or (in aliquots) at -20 °C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens transferrin receptor (TFRC), transcript variant 2
• Database Link:
  Entrez Gene 22042 MouseEntrez Gene 64678 RatEntrez Gene 7037 Human
• Background: CD71 is also known as transferrin receptor(TFRC). Nikinmaa and Schroder (1987) concluded that p90 and TFRC are the same protein: studies using monoclonal antibodies indicated that exhaustive precipitation of radioactively labeled lysates with one antibody removed all activity of lysates with the other. Peptide maps of antigens recognized with both antibodies showed great similarity and indicated that both antibodies react with the same antigen, the human transferrin receptor, but with different antigenic sites of the molecule. TFR is assigned to chromosome 3.
• Synonyms: TfR1, p90, Transferrin receptor protein 1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein, Transmembrane
• Protein Pathways: Endocytosis, Hematopoietic cell lineage