OPCML (C-term) Rabbit Polyclonal Antibody

CAT#: AP23335PU-N

OPCML (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

OPCML Polyclonal Antibody

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  OPCML Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: At 1μg/ml with the appropriate system to detect OPCML in cells and tissues.
  Immunohistochemistry on poraffin sections: At 1-2μg/ml to detect OPCML in formalin fixed and paraffin embedded tissues.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide mapping at the C-terminal of human OPCML
• Specificity: This antibody detects OPCML / OBCAM (C-term).
• Formulation: 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: 0.2ml of distilled water will yield a concentration of 500μg/ml.
• Purification: Immunogen affinity purified
• Gene Name: Homo sapiens opioid binding protein/cell adhesion molecule like (OPCML), transcript variant 1
• Database Link:
  Entrez Gene 116597 RatEntrez Gene 330908 MouseEntrez Gene 4978 Human
• Background: Opioid-binding protein/cell adhesion molecule-like (OPCML), (also called opioid-binding cell adhesion molecule (OBCAM)). OPCML is a member of the IgLON family of immunoglobulin (Ig)domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules, as an excellent candidate for the 11q25 ovarian cancer TSG in EOC. The OPCML gene comprises 7 exons,spans approximately 600 kb, and is transcribed from telomere to centromere . And due to the lack of transmembrane domains necessary for signal transduction, it is improbable that OBCAM acts independently as an opioid receptor; more likely, it plays an important accessory role in opioid receptor function.
• Synonyms: Opioid-binding cell adhesion molecule

Reference Data

• Protein Families: Druggable Genome, Transmembrane