VEGFA (N-term) Rabbit Polyclonal Antibody

CAT#: AP23353PU-N

VEGFA (N-term) rabbit polyclonal antibody, Aff - Purified


USD 405.00

2 Weeks*

Size
    • 100 ug

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Other products for "VEGFA"

Specifications

Product Data
Applications IHC, WB
Recommended Dilution Western blot: Use at 0.1-0.5 μg/ml with the appropriate system to detect VEGF in cells and tissues.
Immunohistochemistry on Paraffin Sections: Use at 0.5-1 μg/ml to detect VEGF in formalin fixed and paraffin embedded tissues. Boiling the sections in 10mM citrate buffer, pH6.0, for 20mins is required.
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide corresponding to a sequence near the N-teminal end of VEGFA (aa 33-48 of Human origin.
Specificity This antibody detects VEGF-A near N-term. No cross reactivity with other proteins.
Formulation 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4
State: Aff - Purified
State: Lyophilized purified IgG fraction
Preservative: 0.05 mg Thimerosal, 0.05 mg Sodium Azide
Reconstitution Method Restore with 0.2 ml of distilled water to a concentration of 0.5 mg/ml.
Purification Immunoaffinity Chromatography
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens vascular endothelial growth factor A (VEGFA), transcript variant 1
Background VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. It may be a major regulator of tumor angiogenesis in vivo.Vascular endothelial growth factor is a mitogen primarily for vascular endothelial cells. It is, however,structurally related to platelet-derived growth factor. VEGF shares homology with the PDGF A chain and B chain, including conservation of all 8 cysteines found in PDGFA and PDGFB. VEGF gene contains 8 exons. Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo.
Synonyms VEGFA, VEGF, VPF, Vascular endothelial growth factor A, Vascular permeability factor
Reference Data
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma, VEGF signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.