Aquaporin 1 (AQP1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP23362PU-N

Aquaporin 1 (AQP1) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of rat tissue sections (kidney) lysis using AQP1 antibody

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  Immunohistochemical analysis of paraffin embedded mammary cancer sections, staining AQP1 in cytoplasm, DAB chromogenic reaction

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: At 0.1-0.5 μg/ml with the appropriate system to detect AQP1 in cells and tissues.
  Immunohistochemistry on paraffin sections: At 0.5-1.0 μg/ml to detect AQP1 in formalin fixed and paraffin embedded tissues.
  
  
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a sequence mapping near the C-terminal of human AQP1
• Specificity: This antibody detects Aquaporin-1 (C-term). No cross reactivity with other proteins.
• Formulation: 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: 0.2ml of distilled water will yield a concentration of 500μg/ml.
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens aquaporin 1 (Colton blood group) (AQP1), transcript variant 1
• Database Link:
  Entrez Gene 11826 MouseEntrez Gene 25240 RatEntrez Gene 358 Human
• Background: Aquaporin 1 is a 28-kD integral protein thought at first to be a breakdown product of the Rh polypeptide but was later shown to be a unique molecule that is abundant in erythrocytes and renal tubules.AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
• Synonyms: AQP-1, CHIP28, Aquaporin-CHIP

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane