NTE (PNPLA6) (1323-1348) Rabbit Polyclonal Antibody
Other products for "PNPLA6"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | Western blot 1 μg/ml. Immunohistochemistry on paraffin sections 1-2 μg/ml. Digestion immunohistochemistry on frozen sections: 1-2 µg/ml. |
Reactivities | Zebrafish |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a sequence at the C-terminal of fish PNPLA6 (1323-1348 amino acid) |
Specificity | This antibody detects NTE at aa 1323-1348. No cross reactivity with other proteins. |
Formulation | 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 State: Aff - Purified State: Lyophilized Ig fraction |
Reconstitution Method | 0.2ml of distilled water will yield a concentration of 500μg/ml. |
Purification | Immunogen affinity purified |
Gene Name | Homo sapiens patatin like phospholipase domain containing 6 (PNPLA6), transcript variant 2 |
Database Link | |
Background | Patatin-like phospholipase domain containing 6 (PNPLA6), also known as Neuropathy target esterase (NTE), is a human gene. Neuropathy target esterase (NTE) is involved in neural development and is the target for neurodegeneration induced by selected organophosphorus pesticides and chemical warfare agents. The genetic or chemical reduction of Nte activity results in a neurological phenotype of hyperactivity in mammals and indicate that EOPF toxicity occurs directly through inhibition of Nte without the requirement for Nte gain of function or aging. |
Synonyms | PNPLA6 |
Reference Data | |
Protein Families | Transmembrane |
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