SCN1B (N-term) Rabbit Polyclonal Antibody

CAT#: AP23388PU-N

SCN1B (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot with SCN1B Polyclonal Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1 μg/ml (Human).
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminal of human SCN1B
• Specificity: This antibody detects SCN1B (N-term).
• Formulation: 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: 0.2ml of distilled water will yield a concentration of 500μg/ml.
• Purification: Immunogen affinity purified
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens sodium channel, voltage gated, type I beta subunit (SCN1B), transcript variant a
• Database Link:
  Entrez Gene 20266 MouseEntrez Gene 29686 RatEntrez Gene 6324 Human
• Background: Voltage-gated sodium (Na+) channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. The complete coding region of Sodium channel,voltage-gated, beta 1(SCN1B) is found in approximately 9.0 kb of genomic DNA and consists of five exons (72 to 749 bp) and four introns (90 bp to 5.5 kb). It is mapped to 19q13.1 and can act as a candidate gene for hereditary disorders affecting membrane excitability. Sodium channel beta1 subunits play important roles in the regulation of sodium channel density and localization and are involved in axo-glial communication at nodes of Ranvier.
• Synonyms: GEFSP1

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Sodium, Transmembrane