LPL (C-term) Rabbit Polyclonal Antibody
Other products for "LPL"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western blot: 1 μg/ml (Bovine). |
Reactivities | Bovine, Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthetic peptide corresponding to a sequence at the C-terminal of human LPL |
Specificity | This antibody detects Lipoprotein lipase (C-term). No cross reactivity with other proteins. |
Formulation | 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 State: Aff - Purified State: Lyophilized Ig fraction |
Reconstitution Method | 0.2ml of distilled water will yield a concentration of 500μg/ml. |
Purification | Immunogen affinity purified |
Database Link | |
Background | Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. Lipoprotein lipase has been difficult to purify, and its protein sequence remained undetermined until it could be deduced from the nucleotide sequence of its cDNA. The gene encodes a protein of 475 amino acids that becomes a mature protein of 448 residues after cleavage of a signal peptide. Analysis of the sequence indicated that human lipoprotein lipase, hepatic lipase, and pancreatic lipase are members of a gene family. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. |
Synonyms | LPL, LIPD, EC=3.1.1.34 |
Reference Data |
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