HSP90AA1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP23429PU-N

HSP90AA1 (C-term) rabbit polyclonal antibody, Aff - Purified

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1μg/ml.
  Immunohistochemistry on paraffin sections: 1μg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human HSP90 (798-815 aa), identical to the related mouse and rat sequence.
• Specificity: This antibody detects Heat Shock Protein 90 / HSP90 (C-term). No cross reactivity with other proteins.
• Formulation: 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: 0.2ml of distilled water will yield a concentration of 500μg/ml
• Purification: Immunoaffinity chromatography
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens heat shock protein 90kDa alpha family class A member 1 (HSP90AA1), transcript variant 2
• Database Link:
  Entrez Gene 15519 MouseEntrez Gene 299331 RatEntrez Gene 3320 Human
• Background: Heat Shock Protein 90 (HSP70) exists in multiple forms in mammalian cells. It has a unique 30-amino acid N terminus instead of the 223-amino acid TP/geldanamycin-binding domain found at the N terminus of full-length HSPCA, which contains 732 amino acids. Functional proteomic screens reveal an essential extracellular role for hsp90-alpha in cancer cell invasiveness.
• Synonyms: HSP90AB1, HSP90B, HSPC2, HSPCB, HSP84, HSP-90, HSP-84, Heat shock protein HSP 90-beta, HSP84, HSP-84, HSP90AA1, HSP90A, HSPC1, HSPCA, HSP86, HSP-86, Renal carcinoma antigen NY-REN-38, Heat shock protein HSP 90-alpha, HSP86, HSP-86

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Antigen processing and presentation, NOD-like receptor signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer