RIP (RIPK1) (N-term) Rabbit Polyclonal Antibody

CAT#: AP23487PU-N

RIP (RIPK1) (N-term) rabbit polyclonal antibody

Product Images

Western blot analysis of RIPK1 in rat kidney tissue lysate with RIPK1 antibody at 1 ug/ml.

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  Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1 - 2 µg/ml.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated
• Specificity: This antibody reacts to the N-term of Receptor-interacting Serine/Threonine Kinase 1 (RIPK1).
• Formulation: PBS containing 0.02% sodium azide as preservative
  State: Liquid purfied Ig fraction
• Concentration: 1 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens receptor interacting serine/threonine kinase 1 (RIPK1), transcript variant 1
• Database Link:
  Entrez Gene 19766 MouseEntrez Gene 306886 RatEntrez Gene 8737 Human
• Background: RIP1 belongs to the RIP subfamily of kinases. The RIP protein contains an N-terminal protein kinase domain, a C-terminal death domain, and a unique internal region. RIP interacts with the death receptors Fas and tumor necrosis receptor 1 (TNFR1) to stimulate apoptosis, SAPK/JNK, and NF-kappaB activation.
• Synonyms: RIPK1

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Apoptosis, Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway