14-3-3 beta (YWHAB) (34-221) Rabbit Polyclonal Antibody

CAT#: AP23583PU-N

14-3-3 beta (YWHAB) (34-221) rabbit polyclonal antibody, Aff - Purified

Product Images

Sample (30 ug of whole cell lysate). A: Raji. 12% SDS PAGE. YWHAB antibody diluted at 1/10000.

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  Human Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using 14-3-3 beta antibody at 1/200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Immunocytochemistry.
  Immunofluorescence: 1/100 - 1/200.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/5000 - 1/20000.
• Reactivities: Human, Zebrafish
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 34 and 221 of Human 14-3-3 beta
• Specificity: This antibody reacts to 14-3-3 beta at aa 34-221.
• Formulation: 0.1 M Tris-glycine, pH 7.0 containing 10% Glycerol as stabilizer and 0.01% Thimerosal as preservative
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta (YWHAB), transcript variant 1
• Database Link:
  Entrez Gene 54401 MouseEntrez Gene 56011 RatEntrez Gene 7529 Human
• Background: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis.
• Synonyms: YWHAB, KCIP-1, Protein 1054

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis