AKT3 (119-136) Rabbit Polyclonal Antibody

CAT#: AP23601PU-N

AKT3 (119-136) rabbit polyclonal antibody


USD 440.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Western Blot: 1 - 2 µg/ml.
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide - KLH conjugated, Synthetic peptide
Specificity A synthetic peptide corresponding to amino acid residues 119-136 of human Akt3. This sequence is identical in human, mouse and rat.
Formulation PBS, 0.02% sodium azide, 0.1 mg/ml BSA.
State: Liquid purfied Ig fraction
Concentration 0.5 mg/ml
Purification Protein G Chromatography
Gene Name Homo sapiens v-akt murine thymoma viral oncogene homolog 3 (AKT3), transcript variant 1
Background AKT3 is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. AKT3 has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1).
Synonyms RAC-PK-gamma, Protein kinase B gamma, PKBG, STK-2
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase
Protein Pathways Acute myeloid leukemia, Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Glioma, Insulin signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Melanoma, mTOR signaling pathway, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Renal cell carcinoma, Small cell lung cancer, T cell receptor signaling pathway, Tight junction, Toll-like receptor signaling pathway, VEGF signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.