TLR7 (900-950) Rabbit Polyclonal Antibody

CAT#: AP23604PU-N

TLR7 (900-950) rabbit polyclonal antibody, Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications FC, IHC, WB
Recommended Dilution Flow Cytometry.
Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Western Blot: 0.5 - 2 µg/ml.
Reactivities Human, Monkey
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide from a portion of amino acids 900-950 of Human TLR7
Specificity This antibody reacts to Toll-like Receptor 7 (TLR7) at aa 900-950.
Formulation PBS
State: Purified
State: Liquid purfied Ig fraction
Stabilizer: 0.05% BSA
Preservative: 0.05% Sodium Azide
Concentration 0.5 mg/ml
Purification Protein G Chromatography
Gene Name Homo sapiens toll like receptor 7 (TLR7)
Background Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFNa secretion, suggesting the importance of TLR7 in virus recognition.
Synonyms Toll-like receptor 7
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Toll-like receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.