TCP1 beta (CCT2) (227-473) Rabbit Polyclonal Antibody

CAT#: AP23626PU-N

TCP1 beta (CCT2) (227-473) rabbit polyclonal antibody, Aff - Purified

Product Images

Sample (30 ug of whole cell lysate). A: Hep G2. B: Raji. 7.5% SDS PAGE. CCT2 antibody diluted at 1/1000.

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  Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/500 - 1/3000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 277 and 473 of Human TCP1 beta
• Specificity: This antibody reacts to T-complex Protein 1, Beta Subunit (CCT2) at aa 277-473.
• Formulation: 0.1 M Tris-glycine, pH 7.0 containing 10% Glycerol and 0.01% Thimerosal
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: 1 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens chaperonin containing TCP1 subunit 2 (CCT2), transcript variant 1
• Database Link:
  Entrez Gene 12461 MouseEntrez Gene 299809 RatEntrez Gene 10576 Human
• Background: This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized.
• Synonyms: 99D8.1, CCT-beta, CCTB, TCP-1 beta

Reference Data

• Protein Families: Druggable Genome