XIAP (75-226) Rabbit Polyclonal Antibody

CAT#: AP23632PU-N

XIAP (75-226) rabbit polyclonal antibody, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ul

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Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution Immunocytochemistry: 1/100 - 1/200.
Immunofluorescence: 1/100 - 1/200.
Immunohistochemistry on Paraffin Sections: 10 µg/ml.
Western Blot: 1/500 - 1/3000.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein fragment containing a sequence corresponding to a region within amino acids 75 and 226 of BIRC4
Specificity This antibody reacts to X-linked Inhibitor Of Apoptosis Protein XIAP (XIAP/BIRC4) at aa 75-226.
Formulation 0.1M Tris-Glycine, pH 7.0 containing 10% Glycerol and 0.01% Thimerosal
State: Aff - Purified
State: Liquid purfied Ig fraction
Concentration lot specific
Purification Immunoaffinity Chromatography
Storage Store the antibody (in aliquots)  at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens X-linked inhibitor of apoptosis (XIAP), transcript variant 1
Background Apoptosis inhibitor 3 (API3) is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, API3 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. API3 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.
Synonyms HILP, API3, XIAP
Reference Data
Protein Families Druggable Genome
Protein Pathways Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.