ACKR3 (311-360) Rabbit Polyclonal Antibody

CAT#: AP23646PU-N

ACKR3 (311-360) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of extracts from COS7 cells, using CXCR7 Antibody. The lane on the right is treated with the synthesized peptide.

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  Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence analysis of COS7 cells, using CXCR7 Antibody. The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Immunofluorescence: 1/100 - 1/500.
  Immunohistochemistry on Paraffin Sections: 1/100.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from human CXCR7 (aa311-360)
• Specificity: This antibody reacts to G Protein-Coupled Receptor RDC1 (CXCR7).
• Formulation: PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM sodium chloride, 0.02% sodium azide as preservative and 50% glycerol as stabilizer
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens atypical chemokine receptor 3 (ACKR3)
• Database Link:
  Entrez Gene 12778 MouseEntrez Gene 84348 RatEntrez Gene 57007 Human
• Background: RDC1 was originally considered to be an Adrenomedullin receptor that binds calcitonin gene-related peptide (CGRP) and adrenomedullin. RDC1 and GPRN1 represent two tissue-specific subtypes of the same 60-kD receptor. RDC1 has the structural characteristics of a chemokine receptor. Recently it has been shown that RDC1 binds to the chemokine CXCL12 and should be considered to be a chemokine receptor.
• Synonyms: CXC-R7, CXCR-7, CMKOR1, GPR-159, RDC1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane