FSH Receptor (FSHR) Rabbit Polyclonal Antibody

CAT#: AP23647PU-N

FSH Receptor (FSHR) rabbit polyclonal antibody

Product Images

Human Ovary: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence analysis of MCF7 cells, using FSHR Antibody. The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: ELISA, IF, IHC
• Recommended Dilution: ELISA: 1/1000.
  Immunofluorescence: 1/100 - 1/500.
  Immunohistochemistry on Paraffin Sections: 1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from Human FSHR. (aa278-327)
  Epitope: Internal
• Specificity: This antibody detects endogenous levels of total FSHR protein.
• Formulation: PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens follicle stimulating hormone receptor (FSHR), transcript variant 1
• Database Link:
  Entrez Gene 2492 Human
• Background: FSHR, a Glycoprotein Hormone Receptor, is required for normal ovarian development and follicle maturation in females. When activated, it stimulates ovarian follicular growth and production of estrogens, initiating a normal menstrual cycle. In males, FSHR is required for the initiation of spermatogenesis and normal sperm production. Two isoforms are produced by alternative splicing.
  Immunogenic peptide has only 57% homology with the corresponding region in mouse and is located in the extracellular domain of the protein.
• Synonyms: Follicle-stimulating hormone receptor, FSH-R, LGR1, Follitropin receptor

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction