ELMO2 (707-720) Goat Polyclonal Antibody

CAT#: AP23813PU-N

ELMO2 (707-720) goat polyclonal antibody, Aff - Purified

Product Images

Antibody staining (2 ug/ml) of Human Brain lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.

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  Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
  Western Blot: 1 - 3 µg/ml.
• Reactivities: Bat, Bovine, Canine, Chicken, Equine, Hamster, Human, Monkey, Mouse, Rabbit, Rat, Xenopus
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from C-terminus of human ELMO2
• Specificity: This antibody reacts to the C-term of ELMO2 (aa 707-720).
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens engulfment and cell motility 2 (ELMO2), transcript variant 1
• Database Link:
  Entrez Gene 140579 MouseEntrez Gene 362271 RatEntrez Gene 63916 Human
• Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
• Synonyms: ELMO 2, ELMO-2, CED12A, CED-12A, KIAA1834