PRODH (84-98) Goat Polyclonal Antibody

CAT#: AP23822PU-N

PRODH (84-98) goat polyclonal antibody, Aff - Purified

Product Images

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

  Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

  Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA: 1/16000.
  Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of human PRODH (NP_057419.2)
• Specificity: This antibody reacts to the internal region of PRODH.
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Upon receipt, store (in aliquots) at -20°C to -80°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens proline dehydrogenase 1 (PRODH), transcript variant 2
• Database Link:
  Entrez Gene 19125 MouseEntrez Gene 5625 Human
• Background: PRODH is a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: PIG6, POX2, Proline oxidase, Proline oxidase 2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Metabolic pathways