SLC12A1 (43-57) Goat Polyclonal Antibody

CAT#: AP23996PU-N

SLC12A1 (43-57) goat polyclonal antibody, Aff - Purified

Product Images

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 - 7.5 µg/ml.
• Reactivities: Human, Monkey
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from positions 43-57 of human SLC12A1 (NP_000329.2)
• Specificity: This antibody reacts to Solute Carrier Family 12 (Sodium/Potassium/Chloride Transporters), Member 1 (SLC12A1) at aa 43-57.
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens solute carrier family 12 member 1 (SLC12A1), transcript variant 1
• Database Link:
  Entrez Gene 6557 Human
• Background: The sodium-potassium-chloride cotransporter isoform 2 is kidney-specific and is found on the apical membrane of the thick ascending limb of Henle's loop and the macula densa. It accounts for most of the NaCl resorption with the stoichiometry of 1Na:1K:2Cl and is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene.
• Synonyms: NKCC2

Reference Data

• Protein Families: Druggable Genome, Transmembrane