Ephrin B2 (EFNB2) pTyr316 Rabbit Polyclonal Antibody

CAT#: AP26036PU-S

Ephrin B2 (EFNB2) pTyr316 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of extracts from HT29 cells, untreated or treated with UV using Ephrin-B2 (Phospho-Tyr316) Antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:500~1:1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide sequence around phosphorylation site of tyrosine 316 (P-V-Y(p)-I-V) derived from Human Ephrin-B2
• Specificity: This antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 316.
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Affinity-chromatography using epitope-specific peptide
• Storage: Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ephrin-B2 (EFNB2)
• Database Link:
  Entrez Gene 13642 MouseEntrez Gene 1948 Human
• Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
• Synonyms: EFNB2, EPLG5, HTKL, LERK5, HTK-L, LERK-5, HTK ligand
• Note: Molecular weight: 37 kDa

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Axon guidance