Cdc25b pSer149 Rabbit Polyclonal Antibody

CAT#: AP26041PU-S

Cdc25b pSer149 rabbit polyclonal antibody, Aff - Purified


USD 230.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications WB
Recommended Dilution Western blot: 1:500 - 1:1000.
Reactivities Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of Serine 149 derived from Mouse Cdc25B.
Specificity This antibody detects endogenous level of Cdc25B protein only when phosphorylated at serine 149.
Formulation Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity-chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Mus musculus cell division cycle 25B (Cdc25b), transcript variant 2
Background Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
Synonyms CDC25HU2
Note Molecular weight: 62
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.