CKII alpha (CSNK2A1) pThr360/pSer362 Rabbit Polyclonal Antibody

CAT#: AP26043PU-S

CKII alpha (CSNK2A1) pThr360/pSer362 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot of CK2a (Phospho- Thr360/Ser362) antibody and CK2a antibody in vitro kinase assay. Both purified ERK2 and CK2 were used. CK2a (Phospho-Thr360/Ser362) antibody could recognize ERK2 phosphorylated wild type CK2a and CK2a when Ser362 was mutated to alanine.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide sequence around phosphorylation site of Threonine 360/Serine 362
• Specificity: This antibody detects endogenous level of CK2 only when phosphorylated at thronine 360.
• Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography using epitope-specific peptide
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens casein kinase 2 alpha 1 (CSNK2A1), transcript variant 2
• Database Link:
  Entrez Gene 12995 MouseEntrez Gene 116549 RatEntrez Gene 1457 Human
• Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
• Synonyms: CSNK2A1, CK2A1, CK II alpha
• Note: Molecular weight: 42 kDa

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase
• Protein Pathways: Adherens junction, Tight junction, Wnt signaling pathway