Maged1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP26048PU-S

Maged1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of extracts from PC12 cells using Melanoma-associated antigen D1 Antibody and the same antibody preincubated with blocking peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:500 - 1:1000.
• Reactivities: Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide with sequence derived from Mouse Melanoma-associated antigen D1.
• Specificity: This antibody detects endogenous level of total Melanoma-associated antigen D1 protein.
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific peptide
• Gene Name: Mus musculus melanoma antigen, family D, 1 (Maged1)
• Database Link:
  Entrez Gene 84469 RatEntrez Gene 94275 Mouse
• Background: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.
• Synonyms: Melanoma-associated antigen D1, MAGED1, NRAGE
• Note: Molecular weight: 95 kDa