Cryptochrome I (CRY1) (551-555) Rabbit Polyclonal Antibody

CAT#: AP26054PU-S

Cryptochrome I (CRY1) (551-555) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of extracts from Mouse brain tissue using CRY1 antibody

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  Western blot analysis of extracts from 293T cells and Rat testis tissue using CRY1 antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500-1/1000.
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Human CRY1.
• Specificity: This antibody detects endogenous level of total CRY1 protein.
• Formulation: Phosphate buffered saline (without Mg²⁺ and Ca²⁺), pH 7.4, 150mM NaCl and 50% glycerol
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography using epitope-specific peptide
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 60 kDa (Predicted)
• Gene Name: Homo sapiens cryptochrome circadian clock 1 (CRY1)
• Database Link:
  Entrez Gene 12952 Mouse
• Background: Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.
• Synonyms: CRY1, PHLL1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Circadian rhythm - mammal