Endo G (ENDOG) Rabbit Polyclonal Antibody

CAT#: AP26343PU-N

Endo G (ENDOG) rabbit polyclonal antibody, Aff - Purified

Product Images

: Western blot analysis of EndoG expression in rat kidney issue lysate.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot (0.5-4 µg/ml).
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 280 of rat EndoG
• Specificity: This antibody recognizes ~35 kDa EndoG.
• Formulation: Phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C. Avoid repeated freezing and thawing.
• Stability: Shelf life: One year from despatch.
• Gene Name: Homo sapiens endonuclease G (ENDOG)
• Database Link:
  Entrez Gene 13804 MouseEntrez Gene 362100 RatEntrez Gene 2021 Human
• Background: Endonuclease G (EndoG) is a mitochondrion-specific nuclease that specifically activated by apoptotic stimuli and translocates to the nucleus during apoptosis. In nucleus, EndoG induces nucleosomal fragmentation of DNA independent of caspase and DFF/CAD.
• Synonyms: ENDOG

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Apoptosis