Occludin (OCLN) (358-504) Guinea Pig Polyclonal Antibody

CAT#: AP26410PU-N

Occludin (OCLN) (358-504) guinea pig polyclonal antibody, Purified


USD 405.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution Immunohistochemistry on Frozen Sections: The typical starting working dilution is 1/50.
Immunoflourescence: The typical starting working dilution is 1/50.
Western blot: The typical starting working dilution is 1/50.
Reactivities Canine, Human, Mouse, Rat
Host Guinea Pig
Isotype Ig
Clonality Polyclonal
Immunogen Recombinant Human Occludin (aa 358-504)
Specificity

The polyclonal antibody reacts with Occludin.

Formulation PBS
State: Purified
State: Liquid 0.2 µm filtered Ig fraction
Stabilizer: 0.1% BSA
Preservative: 0.02% Sodium Azide
Concentration 0.1 mg/ml
Purification Protein A Chromatography
Background Occludin is an integral membrane protein specifically associated with tight junctions. These specialized regions of the plasma membrane prevent the diffusion of dissolved molecules between adjacent epithelial cells, seal off body cavities such as intestine or stomach lumen and prevent the diffusion of membrane proteins and glycolipids between the apical and basolateral regions of the plasma membrane. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-characterized tight junction protein zona occludens 1 (ZO-1).
Synonyms OCLN
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.