KCNN4 (227-239) Goat Polyclonal Antibody

CAT#: AP31012PU-N

KCNN4 (227-239) goat polyclonal antibody, Aff - Purified


USD 440.00

2 Weeks*

Size
    • 50 ug

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Specifications

Product Data
Applications IHC
Recommended Dilution Immunohistochemistry on Paraffin Sections: 3.75 - 7.5 µg/ml.
Reactivities Bovine, Canine, Human, Rabbit
Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide from positions 227-239 of human KCNN4 (NP_002241.1)
Specificity This antibody reacts to Potassium Intermediate/Small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (Kcnn4) at aa 227-239.
Formulation Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
State: Aff - Purified
State: Liquid purfied Ig fraction
Concentration lot specific
Purification Immunoaffinity Chromatography
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 (KCNN4)
Background Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Synonyms KCNN4, IK1, IKCA1, KCA4, SK4, KCa3.1, Putative Gardos channel
Note The Kcnn4 synonym, IK1, also is used to describe the cardiac inward rectifier current.
Reference Data
Protein Families Druggable Genome, Ion Channels: Potassium, Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.